Quinoline, 4-chloro-7-fluoro-2-methyl-

Quinoline, 4-chloro-7-fluoro-2-methyl- - Names and Identifiers

Name	4-Chloro-7-fluoro-2-methylquinoline
Synonyms	4-CHLORO-7-FLUOROQUINALDINE 4-CHLORO-7-FLUORO-2-METHYLQUINOLINE 4-Chloro-7-fluoro-2-methylquinoline Quinoline, 4-chloro-7-fluoro-2-methyl-
CAS	18529-04-9
InChI	InChI=1/C10H7ClFN/c1-6-4-9(11)8-3-2-7(12)5-10(8)13-6/h2-5H,1H3

Quinoline, 4-chloro-7-fluoro-2-methyl- - Physico-chemical Properties

Molecular Formula	C10H7ClFN
Molar Mass	195.62
Density	1.311
Boling Point	270℃
Flash Point	117℃
Vapor Presure	0.0117mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.612
MDL	MFCD00272333

Quinoline, 4-chloro-7-fluoro-2-methyl- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

Quinoline, 4-chloro-7-fluoro-2-methyl- - Introduction

It is an organic compound, its chemical formula is C10H6ClFN, the structure has a chlorine atom, a fluorine atom and a methyl group substituted in the quinoline ring.

The properties of this compound are as follows:
1. Appearance: White to light yellow solid.
2. Melting Point: its melting point range of 65-71 ℃.
3. Solubility: It is soluble in organic solvents such as alcohols, ethers and ketones, but has low solubility in water.
4. Chemical properties: it has certain stability to oxidizing reagents and strong acids.

In practical applications, it has some important uses:
1. Pesticide intermediates: It is a synthetic intermediate of some fungicides, herbicides and pesticides.
2. Photoelectric materials: The compound has fluorescent properties and can be used for the research and development of optoelectronic device materials.
3. Fluorescent probe: It can be used as a fluorescent marker for cells, molecular probes and dyes.

The preparation method generally includes the following steps:
1. First, 4-chloro-7-fluoroquinoline was synthesized by chemical synthesis.
2. Then, under appropriate conditions, add a methylating agent (such as methyl bromide) to 4-chloro-7-fluoroquinoline to achieve the methylation reaction.

When using and handling, you need to pay attention to the following safety information:
1. Avoid inhalation and contact with skin: This compound may cause irritation and damage to the skin, eyes and respiratory tract, so avoid inhalation and contact with skin during operation.
2. Use personal protective equipment: Wear protective gloves, goggles and chemical protective clothing when handling the compound.
3. Avoid contact with oxidants: It has a certain degree of oxidation and avoids contact with oxidants and other substances that are prone to chemical reactions.
4. Storage precautions: Store the compound in a dry, ventilated and well-sealed container, away from fire and high temperature.

When using and handling any chemicals, please be sure to follow the correct laboratory operating procedures, and carefully read and comply with relevant safety technical instructions and regulations.

Last Update：2024-04-10 22:29:15